Ribonuclease 4
|
Rnase4 |
Q9JJH1 |
Amyotrophic Lateral Sclerosis
|
Soo, K. Y. et al. (Acta Neuropathol, 2015)
|
Profilin-2
|
Pfn2 |
Q9JJV2 |
Amyotrophic Lateral Sclerosis
|
Figley, M. D. et al. (J Neurosci, 2014)
|
Metalloproteinase inhibitor 3
|
Timp3 |
P39876 |
Amyotrophic Lateral Sclerosis
|
Lee, J. K. et al. (Neurobiol Dis, 2008)
|
Metalloproteinase inhibitor 3
|
Timp3 |
P48032 |
Amyotrophic Lateral Sclerosis
|
Lee, J. K. et al. (Neurobiol Dis, 2008)
|
Glial cell line-derived neurotrophic factor
|
Gdnf |
P48540 |
Amyotrophic Lateral Sclerosis
|
Mitsuma, N. et al. (Brain Res, 1999), Mohajeri, M. H. et al. (Hum Gene Ther, 1999), Keir, S. D. et al. (J Neurovirol, 2001), Wang, L. J. et al. (J Neurosci, 2002), Klein, S. M. et al. (Hum Gene Ther, 2005), Suzuki, M. et al. (PLoS One, 2007), Suzuki, M. et al. (Mol Ther, 2008), Ciriza, J. et al. (Restor Neurol Neurosci, 2008), Park, S. et al. (Exp Mol Med, 2009), Ryu, H. et al. (Lab Invest, 2011), Moreno-Igoa, M. et al. (Restor Neurol Neurosci, 2012), Thau, N. et al. (Neurobiol Dis, 2012), Krakora, D. et al. (Mol Ther, 2013), Battaglia, G. et al. (Neurobiol Dis, 2015), Thomsen, G. M. et al. (Gene Ther, 2017), Bohn, M. C. (Biochem Pharmacol, 1999)
|
Lumican
|
LUM |
M3Y826 |
Amyotrophic Lateral Sclerosis
|
Daoud, H. et al. (Arch Neurol, 2011)
|
Valosin containing protein
|
VCP |
M3XZQ1 |
Amyotrophic Lateral Sclerosis
|
Ishigaki, S. et al. (J Biol Chem, 2004), Liscic, R. M. et al. (Eur J Neurol, 2008), van Swieten, J. C. et al. (Lancet Neurol, 2008), Johnson, J. O. et al. (Neuron, 2010), de Carvalho, M. et al. (Curr Opin Neurol, 2011), Walker, A. K. et al. (IUBMB Life, 2011), Nalbandian, A. et al. (J Mol Neurosci, 2011), Majounie, E. et al. (Neurobiol Aging, 2012), Shi, Z. et al. (Eur J Neurol, 2012), Koppers, M. et al. (Neurobiol Aging, 2012), Tiloca, C. et al. (Neurobiol Aging, 2012), Williams, K. L. et al. (Neurobiol Aging, 2012), Yi, L. et al. (Hum Mol Genet, 2012), Fecto, F. et al. (Muscle Nerve, 2012), Van Langenhove, T. et al. (Ann Med, 2012), Morris, H. R. et al. (Curr Neurol Neurosci Rep, 2012), Abramzon, Y. et al. (Neurobiol Aging, 2012), Belzil, V. V. et al. (Eur J Hum Genet, 2013), Yin, H. Z. et al. (Cell Death Dis, 2012), Nalbandian, A. et al. (PLoS One, 2012), Arhzaouy, K. et al. (PLoS One, 2012), Zou, Z. Y. et al. (Neurobiol Aging, 2013), Gonzalez-Perez, P. et al. (Neurology, 2012), Ching, J. K. et al. (Hum Mol Genet, 2013), Cloutier, P. et al. (PLoS Genet, 2013), Bartolome, F. et al. (Neuron, 2013), McGoldrick, P. et al. (Biochim Biophys Acta, 2013), Neumann, M. (Rev Neurol (Paris), 2013), Kimura, Y. et al. (Genes Cells, 2013), Seelen, M. et al. (Neurobiol Aging, 2014), Baron, Y. et al. (BMC Biol, 2014), McCluskey, L. et al. (J Neurol Sci, 2014), Gonzalez, M. A. et al. (Brain, 2014), Hirano, M. et al. (Neurobiol Aging, 2015), Ayaki, T. et al. (Acta Neuropathol Commun, 2014), Kwok, C. T. et al. (J Neurol Sci, 2015), Barthelme, D. et al. (Protein Sci, 2015), Hirano, M. et al. (Eur Neurol, 2017)
|
Transitional endoplasmic reticulum ATPase
|
Vcp |
Q01853 |
Amyotrophic Lateral Sclerosis
|
Ishigaki, S. et al. (J Biol Chem, 2004), Liscic, R. M. et al. (Eur J Neurol, 2008), van Swieten, J. C. et al. (Lancet Neurol, 2008), Johnson, J. O. et al. (Neuron, 2010), de Carvalho, M. et al. (Curr Opin Neurol, 2011), Walker, A. K. et al. (IUBMB Life, 2011), Nalbandian, A. et al. (J Mol Neurosci, 2011), Majounie, E. et al. (Neurobiol Aging, 2012), Shi, Z. et al. (Eur J Neurol, 2012), Koppers, M. et al. (Neurobiol Aging, 2012), Tiloca, C. et al. (Neurobiol Aging, 2012), Williams, K. L. et al. (Neurobiol Aging, 2012), Yi, L. et al. (Hum Mol Genet, 2012), Fecto, F. et al. (Muscle Nerve, 2012), Van Langenhove, T. et al. (Ann Med, 2012), Morris, H. R. et al. (Curr Neurol Neurosci Rep, 2012), Abramzon, Y. et al. (Neurobiol Aging, 2012), Belzil, V. V. et al. (Eur J Hum Genet, 2013), Yin, H. Z. et al. (Cell Death Dis, 2012), Nalbandian, A. et al. (PLoS One, 2012), Arhzaouy, K. et al. (PLoS One, 2012), Zou, Z. Y. et al. (Neurobiol Aging, 2013), Gonzalez-Perez, P. et al. (Neurology, 2012), Ching, J. K. et al. (Hum Mol Genet, 2013), Cloutier, P. et al. (PLoS Genet, 2013), Bartolome, F. et al. (Neuron, 2013), McGoldrick, P. et al. (Biochim Biophys Acta, 2013), Neumann, M. (Rev Neurol (Paris), 2013), Kimura, Y. et al. (Genes Cells, 2013), Seelen, M. et al. (Neurobiol Aging, 2014), Baron, Y. et al. (BMC Biol, 2014), McCluskey, L. et al. (J Neurol Sci, 2014), Gonzalez, M. A. et al. (Brain, 2014), Hirano, M. et al. (Neurobiol Aging, 2015), Ayaki, T. et al. (Acta Neuropathol Commun, 2014), Kwok, C. T. et al. (J Neurol Sci, 2015), Barthelme, D. et al. (Protein Sci, 2015), Hirano, M. et al. (Eur Neurol, 2017)
|
Transitional endoplasmic reticulum ATPase
|
Vcp |
P46462 |
Amyotrophic Lateral Sclerosis
|
Ishigaki, S. et al. (J Biol Chem, 2004), Liscic, R. M. et al. (Eur J Neurol, 2008), van Swieten, J. C. et al. (Lancet Neurol, 2008), Johnson, J. O. et al. (Neuron, 2010), de Carvalho, M. et al. (Curr Opin Neurol, 2011), Walker, A. K. et al. (IUBMB Life, 2011), Nalbandian, A. et al. (J Mol Neurosci, 2011), Majounie, E. et al. (Neurobiol Aging, 2012), Shi, Z. et al. (Eur J Neurol, 2012), Koppers, M. et al. (Neurobiol Aging, 2012), Tiloca, C. et al. (Neurobiol Aging, 2012), Williams, K. L. et al. (Neurobiol Aging, 2012), Yi, L. et al. (Hum Mol Genet, 2012), Fecto, F. et al. (Muscle Nerve, 2012), Van Langenhove, T. et al. (Ann Med, 2012), Morris, H. R. et al. (Curr Neurol Neurosci Rep, 2012), Abramzon, Y. et al. (Neurobiol Aging, 2012), Belzil, V. V. et al. (Eur J Hum Genet, 2013), Yin, H. Z. et al. (Cell Death Dis, 2012), Nalbandian, A. et al. (PLoS One, 2012), Arhzaouy, K. et al. (PLoS One, 2012), Zou, Z. Y. et al. (Neurobiol Aging, 2013), Gonzalez-Perez, P. et al. (Neurology, 2012), Ching, J. K. et al. (Hum Mol Genet, 2013), Cloutier, P. et al. (PLoS Genet, 2013), Bartolome, F. et al. (Neuron, 2013), McGoldrick, P. et al. (Biochim Biophys Acta, 2013), Neumann, M. (Rev Neurol (Paris), 2013), Kimura, Y. et al. (Genes Cells, 2013), Seelen, M. et al. (Neurobiol Aging, 2014), Baron, Y. et al. (BMC Biol, 2014), McCluskey, L. et al. (J Neurol Sci, 2014), Gonzalez, M. A. et al. (Brain, 2014), Hirano, M. et al. (Neurobiol Aging, 2015), Ayaki, T. et al. (Acta Neuropathol Commun, 2014), Kwok, C. T. et al. (J Neurol Sci, 2015), Barthelme, D. et al. (Protein Sci, 2015), Hirano, M. et al. (Eur Neurol, 2017)
|
Neurexin-1
|
Nrxn1 |
Q63372 |
Amyotrophic Lateral Sclerosis
|
Schymick, J. C. et al. (Lancet Neurol, 2007)
|
Neurexin-1
|
Nrxn1 |
Q9CS84 |
Amyotrophic Lateral Sclerosis
|
Schymick, J. C. et al. (Lancet Neurol, 2007)
|
Transforming growth factor beta-2
|
Tgfb2 |
P27090 |
Amyotrophic Lateral Sclerosis
|
Day, W. A. et al. (Neurobiol Dis, 2005)
|
Synaptic functional regulator FMR1
|
Fmr1 |
P35922 |
Amyotrophic Lateral Sclerosis
|
|
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
|
Pin1 |
Q9QUR7 |
Amyotrophic Lateral Sclerosis
|
Rudrabhatla, P. et al. (J Biol Chem, 2008), Rudrabhatla, P. et al. (J Neurosci, 2009)
|
Insulin-like growth factor-binding protein 7
|
Igfbp7 |
Q61581 |
Amyotrophic Lateral Sclerosis
|
Wang, G. et al. (Mol Neurodegener, 2015)
|
Ceramide glucosyltransferase
|
Ugcg |
O88693 |
Amyotrophic Lateral Sclerosis
|
Henriques, A. et al. (Hum Mol Genet, 2015)
|
Sortilin
|
Sort1 |
O54861 |
Amyotrophic Lateral Sclerosis
|
Belzil, V. V. et al. (Neurobiol Aging, 2012)
|
Latexin
|
Lxn |
P70202 |
Amyotrophic Lateral Sclerosis
|
Montuschi, A. et al. (J Neurol Neurosurg Psychiatry, 2015)
|
Latexin
|
Lxn |
Q64361 |
Amyotrophic Lateral Sclerosis
|
Montuschi, A. et al. (J Neurol Neurosurg Psychiatry, 2015)
|
Triggering receptor expressed on myeloid cells 2
|
Trem2 |
Q99NH8 |
Amyotrophic Lateral Sclerosis
|
Rayaprolu, S. et al. (Mol Neurodegener, 2013), Cady, J. et al. (JAMA Neurol, 2014), Kleinberger, G. et al. (Sci Transl Med, 2014), Lue, L. F. et al. (Brain Pathol, 2015), Lue, L. F. et al. (Neuroscience, 2015), Ortega-Cubero, S. et al. (Parkinsonism Relat Disord, 2015), Lill, C. M. et al. (Alzheimers Dement, 2015), Chen, X. et al. (J Neurol Sci, 2015)
|
DNA (cytosine-5)-methyltransferase 3A
|
Dnmt3a |
O88508 |
Amyotrophic Lateral Sclerosis
|
Chestnut, B. A. et al. (J Neurosci, 2011)
|