| Signal peptide(a) |
Y |
Secretome P(b) |
0.916 |
| Function |
TGF-beta 2 has suppressive effects on interleukin-2 dependent T-cell growth. |
| GO - Molecular function |
- amyloid-beta binding : ISS:UniProtKB
- cytokine activity : IBA:GO_Central
- growth factor activity : TAS:UniProtKB
- protein heterodimerization activity : ISO:MGI
- protein homodimerization activity : ISS:UniProtKB
- protein N-terminus binding : ISO:MGI
- signaling receptor binding : ISS:UniProtKB
- transforming growth factor beta receptor binding : ISS:UniProtKB
- type II transforming growth factor beta receptor binding : ISS:UniProtKB
- type III transforming growth factor beta receptor binding : ISS:AgBase
|
| GO - Biological process |
- activation of protein kinase activity : ISS:UniProtKB
- ascending aorta morphogenesis : IMP:BHF-UCL
- atrial septum morphogenesis : IMP:BHF-UCL
- atrial septum primum morphogenesis : IMP:BHF-UCL
- atrioventricular valve morphogenesis : IMP:BHF-UCL
- axon guidance : IMP:MGI
- blood vessel development : IMP:MGI
- blood vessel remodeling : IMP:MGI
- BMP signaling pathway : IBA:GO_Central
- cardiac epithelial to mesenchymal transition : ISS:UniProtKB
- cardiac left ventricle morphogenesis : TAS:DFLAT
- cardiac muscle cell proliferation : ISS:UniProtKB
- cardiac right ventricle morphogenesis : IMP:BHF-UCL
- cardioblast differentiation : ISS:UniProtKB
- cartilage condensation : IGI:MGI
- cell cycle arrest : ISS:UniProtKB
- cell death : ISS:UniProtKB
- cell migration : ISS:UniProtKB
- cell morphogenesis : ISS:UniProtKB
- cell-cell junction organization : ISS:UniProtKB
- collagen fibril organization : ISS:UniProtKB
- cranial skeletal system development : IMP:BHF-UCL
- dopamine biosynthetic process : IMP:UniProtKB
- embryonic digestive tract development : ISS:AgBase
- embryonic limb morphogenesis : IMP:BHF-UCL
- embryonic neurocranium morphogenesis : ISO:MGI
- endocardial cushion fusion : IMP:BHF-UCL
- endocardial cushion morphogenesis : IMP:BHF-UCL
- epithelial to mesenchymal transition : ISS:UniProtKB
- extracellular matrix organization : IMP:MGI
- extrinsic apoptotic signaling pathway : ISS:BHF-UCL
- eye development : ISS:UniProtKB
- face morphogenesis : IEP:UniProtKB
- glial cell migration : ISS:UniProtKB
- hair follicle development : IMP:UniProtKB
- hair follicle morphogenesis : IMP:UniProtKB
- heart development : IMP:MGI
- heart morphogenesis : ISS:UniProtKB
- heart valve morphogenesis : IMP:BHF-UCL
- hemopoiesis : IMP:UniProtKB
- inner ear development : IMP:BHF-UCL
- kidney development : IMP:BHF-UCL
- male gonad development : IMP:BHF-UCL
- membranous septum morphogenesis : IMP:BHF-UCL
- negative regulation of alkaline phosphatase activity : ISS:UniProtKB
- negative regulation of angiogenesis : ISO:MGI
- negative regulation of apoptotic process : ISO:MGI
- negative regulation of cartilage development : IMP:MGI
- negative regulation of cell growth : ISS:AgBase
- negative regulation of cell proliferation : ISS:UniProtKB
- negative regulation of epithelial cell proliferation : ISS:UniProtKB
- negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation : IMP:BHF-UCL
- negative regulation of gene expression : IDA:UniProtKB
- negative regulation of immune response : ISO:MGI
- negative regulation of keratinocyte differentiation : NAS:UniProtKB
- negative regulation of macrophage cytokine production : ISS:UniProtKB
- negative regulation of Ras protein signal transduction : IMP:BHF-UCL
- negative regulation of release of sequestered calcium ion into cytosol : ISO:MGI
- neural retina development : IMP:BHF-UCL
- neural tube closure : IMP:BHF-UCL
- neuron development : IMP:UniProtKB
- neuron fate commitment : IDA:MGI
- neutrophil chemotaxis : ISS:UniProtKB
- outflow tract morphogenesis : TAS:DFLAT
- outflow tract septum morphogenesis : IMP:BHF-UCL
- pathway-restricted SMAD protein phosphorylation : IDA:BHF-UCL
- pharyngeal arch artery morphogenesis : IMP:BHF-UCL
- positive regulation of activation-induced cell death of T cells : IDA:MGI
- positive regulation of apoptotic process : ISO:MGI
- positive regulation of cardioblast differentiation : ISS:UniProtKB
- positive regulation of cell adhesion mediated by integrin : ISS:UniProtKB
- positive regulation of cell cycle : IMP:UniProtKB
- positive regulation of cell division : IEA:UniProtKB-KW
- positive regulation of cell growth : ISS:UniProtKB
- positive regulation of cell migration : ISO:MGI
- positive regulation of cell proliferation : ISS:UniProtKB
- positive regulation of epithelial cell migration : ISS:UniProtKB
- positive regulation of epithelial to mesenchymal transition : ISS:UniProtKB
- positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation : IMP:BHF-UCL
- positive regulation of extracellular matrix disassembly : IDA:UniProtKB
- positive regulation of extrinsic apoptotic signaling pathway in absence of ligand : IDA:MGI
- positive regulation of gene expression : IDA:UniProtKB
- positive regulation of GTP binding : IDA:UniProtKB
- positive regulation of heart contraction : ISS:UniProtKB
- positive regulation of immune response : ISS:UniProtKB
- positive regulation of integrin biosynthetic process : ISS:UniProtKB
- positive regulation of neuron apoptotic process : ISS:UniProtKB
- positive regulation of Notch signaling pathway : ISO:MGI
- positive regulation of ossification : ISS:AgBase
- positive regulation of pathway-restricted SMAD protein phosphorylation : IBA:GO_Central
- positive regulation of phosphatidylinositol 3-kinase signaling : ISS:UniProtKB
- positive regulation of pri-miRNA transcription by RNA polymerase II : ISO:MGI
- positive regulation of protein localization to nucleus : IDA:UniProtKB
- positive regulation of protein secretion : ISS:UniProtKB
- positive regulation of stress-activated MAPK cascade : ISS:UniProtKB
- positive regulation of timing of catagen : ISS:UniProtKB
- protein phosphorylation : ISS:UniProtKB
- pulmonary valve morphogenesis : IMP:BHF-UCL
- regulation of actin cytoskeleton organization : IDA:UniProtKB
- regulation of apoptotic process : IMP:MGI
- regulation of apoptotic process involved in outflow tract morphogenesis : IMP:BHF-UCL
- regulation of cell proliferation : IBA:GO_Central
- regulation of extracellular matrix organization : IMP:MGI
- regulation of MAPK cascade : IBA:GO_Central
- regulation of timing of catagen : ISS:UniProtKB
- regulation of transforming growth factor beta2 production : ISS:UniProtKB
- response to drug : ISS:UniProtKB
- response to estrogen : ISO:MGI
- response to hypoxia : ISS:UniProtKB
- response to progesterone : ISS:UniProtKB
- response to wounding : ISS:AgBase
- salivary gland morphogenesis : ISS:AgBase
- secondary palate development : IMP:BHF-UCL
- skeletal system development : IMP:BHF-UCL
- SMAD protein signal transduction : ISS:BHF-UCL
- somatic stem cell division : IDA:UniProtKB
- substantia propria of cornea development : IMP:BHF-UCL
- transforming growth factor beta receptor signaling pathway : ISS:UniProtKB
- uterus development : IMP:BHF-UCL
- ventricular septum morphogenesis : IMP:BHF-UCL
- ventricular trabecula myocardium morphogenesis : IMP:BHF-UCL
- wound healing : ISS:UniProtKB
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