Insulin-like growth factor-binding protein 7 (Q61581)

Uniprot ID Q61581
Protein Name Insulin-like growth factor-binding protein 7
Gene Name Igfbp7
Species Mus musculus (Mouse)
Signal peptide(a) Y Secretome P(b) 0.0
Function Binds IGF-I and IGF-II with a relatively low affinity Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion (By similarity). .
GO - Molecular function
  • insulin-like growth factor binding : IEA:InterPro
GO - Biological process
  • cell adhesion : ISS:UniProtKB
  • inner ear development : IDA:MGI
  • regulation of cell growth : IEA:InterPro
  • regulation of steroid biosynthetic process : ISO:MGI
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(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.