| Signal peptide(a) |
Y |
Secretome P(b) |
0.876 |
| Function |
Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake. |
| GO - Molecular function |
- glial cell-derived neurotrophic factor receptor binding : ISO:MGI
- growth factor activity : ISO:MGI
- protein homodimerization activity : ISS:UniProtKB
- receptor ligand activity : ISO:MGI
- receptor tyrosine kinase binding : ISO:MGI
- transforming growth factor beta receptor binding : TAS:MGI
|
| GO - Biological process |
- branching involved in ureteric bud morphogenesis : IDA:MGI
- cell population proliferation : ISO:MGI
- cellular response to dexamethasone stimulus : ISO:MGI
- commissural neuron axon guidance : IGI:ARUK-UCL
- dorsal spinal cord development : IMP:ARUK-UCL
- embryonic organ development : IMP:ARUK-UCL
- enteric nervous system development : IDA:UniProtKB
- mesenchymal to epithelial transition involved in metanephros morphogenesis : IEP:UniProtKB
- metanephros development : IMP:UniProtKB
- mRNA stabilization : ISS:UniProtKB
- negative regulation of extrinsic apoptotic signaling pathway in absence of ligand : ISO:MGI
- negative regulation of neuron apoptotic process : IMP:MGI
- nervous system development : IMP:MGI
- neural crest cell migration : ISS:UniProtKB
- neural crest cell migration involved in autonomic nervous system development : ISO:MGI
- neuron differentiation : ISO:MGI
- neuron projection development : ISS:UniProtKB
- organ induction : IGI:MGI
- peripheral nervous system development : IMP:MGI
- peristalsis : IMP:UniProtKB
- positive regulation of branching involved in ureteric bud morphogenesis : IMP:UniProtKB
- positive regulation of cell differentiation : ISO:MGI
- positive regulation of cell population proliferation : ISO:MGI
- positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis : IMP:UniProtKB
- positive regulation of monooxygenase activity : ISS:UniProtKB
- positive regulation of peptidyl-tyrosine phosphorylation : ISO:MGI
- positive regulation of transcription by RNA polymerase II : ISS:UniProtKB
- positive regulation of ureteric bud formation : ISS:UniProtKB
- postganglionic parasympathetic fiber development : IMP:UniProtKB
- postsynaptic membrane organization : IDA:MGI
- regulation of dopamine uptake involved in synaptic transmission : ISS:UniProtKB
- regulation of gene expression : ISO:MGI
- regulation of morphogenesis of a branching structure : IDA:MGI
- regulation of semaphorin-plexin signaling pathway : IGI:ARUK-UCL
- regulation of ureteric bud formation : ISO:MGI
- response to wounding : ISO:MGI
- sympathetic nervous system development : IMP:UniProtKB
- transforming growth factor beta receptor signaling pathway : TAS:MGI
- transmembrane receptor protein tyrosine kinase signaling pathway : TAS:MGI
- ureteric bud development : IDA:MGI
- ureteric bud formation : IMP:UniProtKB
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