Valosin containing protein (M3XZQ1)

Uniprot ID M3XZQ1
Protein Name Valosin containing protein
Gene Name VCP
Species Mustela putorius furo (European domestic ferret) (Mustela furo)
Signal peptide(a) N Secretome P(b) 0.265
Function
GO - Molecular function
  • ADP binding : IEA:Ensembl
  • ATP binding : IEA:UniProtKB-KW
  • ATPase activity : IEA:Ensembl
  • BAT3 complex binding : IEA:Ensembl
  • deubiquitinase activator activity : IEA:Ensembl
  • identical protein binding : IEA:Ensembl
  • K48-linked polyubiquitin modification-dependent protein binding : IEA:Ensembl
  • MHC class I protein binding : IEA:Ensembl
  • protein domain specific binding : IEA:Ensembl
  • protein phosphatase binding : IEA:Ensembl
  • ubiquitin protein ligase binding : IEA:Ensembl
  • ubiquitin-specific protease binding : IEA:Ensembl
GO - Biological process
  • activation of cysteine-type endopeptidase activity involved in apoptotic process : IEA:Ensembl
  • aggresome assembly : IEA:Ensembl
  • ATP metabolic process : IEA:Ensembl
  • autophagosome maturation : IEA:Ensembl
  • double-strand break repair : IEA:Ensembl
  • endoplasmic reticulum stress-induced pre-emptive quality control : IEA:Ensembl
  • endosome to lysosome transport via multivesicular body sorting pathway : IEA:Ensembl
  • ER-associated misfolded protein catabolic process : IEA:Ensembl
  • flavin adenine dinucleotide catabolic process : IEA:Ensembl
  • NADH metabolic process : IEA:Ensembl
  • positive regulation of ATP biosynthetic process : IEA:Ensembl
  • positive regulation of canonical Wnt signaling pathway : IEA:Ensembl
  • positive regulation of Lys63-specific deubiquitinase activity : IEA:Ensembl
  • positive regulation of mitochondrial membrane potential : IEA:Ensembl
  • positive regulation of oxidative phosphorylation : IEA:Ensembl
  • positive regulation of proteasomal ubiquitin-dependent protein catabolic process : IEA:Ensembl
  • positive regulation of protein complex assembly : IEA:Ensembl
  • protein hexamerization : IEA:Ensembl
  • protein N-linked glycosylation via asparagine : IEA:Ensembl
  • protein ubiquitination : IEA:Ensembl
  • regulation of aerobic respiration : IEA:Ensembl
  • retrograde protein transport, ER to cytosol : IEA:Ensembl
  • translesion synthesis : IEA:Ensembl
  • ubiquitin-dependent ERAD pathway : IEA:Ensembl
  • viral genome replication : IEA:Ensembl
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.