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M3XZQ1

Valosin containing protein (M3XZQ1)

Uniprot ID M3XZQ1
Protein Name Valosin containing protein
Gene Name VCP
Species Mustela putorius furo (European domestic ferret) (Mustela furo)
Basic Information Experiments (1) Disease (14) Interactions
Signal peptide(a) N Secretome P(b) 0.265
Function
GO - Molecular function
  • ADP binding : IEA:Ensembl
  • ATP binding : IEA:UniProtKB-KW
  • ATPase activity : IEA:Ensembl
  • BAT3 complex binding : IEA:Ensembl
  • deubiquitinase activator activity : IEA:Ensembl
  • identical protein binding : IEA:Ensembl
  • K48-linked polyubiquitin modification-dependent protein binding : IEA:Ensembl
  • MHC class I protein binding : IEA:Ensembl
  • protein domain specific binding : IEA:Ensembl
  • protein phosphatase binding : IEA:Ensembl
  • ubiquitin protein ligase binding : IEA:Ensembl
  • ubiquitin-specific protease binding : IEA:Ensembl
GO - Biological process
  • activation of cysteine-type endopeptidase activity involved in apoptotic process : IEA:Ensembl
  • aggresome assembly : IEA:Ensembl
  • ATP metabolic process : IEA:Ensembl
  • autophagosome maturation : IEA:Ensembl
  • double-strand break repair : IEA:Ensembl
  • endoplasmic reticulum stress-induced pre-emptive quality control : IEA:Ensembl
  • endosome to lysosome transport via multivesicular body sorting pathway : IEA:Ensembl
  • ER-associated misfolded protein catabolic process : IEA:Ensembl
  • flavin adenine dinucleotide catabolic process : IEA:Ensembl
  • NADH metabolic process : IEA:Ensembl
  • positive regulation of ATP biosynthetic process : IEA:Ensembl
  • positive regulation of canonical Wnt signaling pathway : IEA:Ensembl
  • positive regulation of Lys63-specific deubiquitinase activity : IEA:Ensembl
  • positive regulation of mitochondrial membrane potential : IEA:Ensembl
  • positive regulation of oxidative phosphorylation : IEA:Ensembl
  • positive regulation of proteasomal ubiquitin-dependent protein catabolic process : IEA:Ensembl
  • positive regulation of protein complex assembly : IEA:Ensembl
  • protein hexamerization : IEA:Ensembl
  • protein N-linked glycosylation via asparagine : IEA:Ensembl
  • protein ubiquitination : IEA:Ensembl
  • regulation of aerobic respiration : IEA:Ensembl
  • retrograde protein transport, ER to cytosol : IEA:Ensembl
  • translesion synthesis : IEA:Ensembl
  • ubiquitin-dependent ERAD pathway : IEA:Ensembl
  • viral genome replication : IEA:Ensembl
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.