Gliome Database

Protein Name	Gene Name	Uniprot ID	Disease Name	References
Brain-derived neurotrophic factor	Bdnf	P21237	Motor Neuron Disease	Sakamoto, T. et al. (J Neurosci Res, 2003)
Metallothionein-3	Mt3	P28184	Motor Neuron Disease	Sakamoto, T. et al. (Neuroreport, 2003), Watabe, K. et al. (Neuropathology, 2005)
Ciliary neurotrophic factor	Cntf	P20294	Motor Neuron Disease	Sakamoto, T. et al. (J Neurosci Res, 2003) and 2 others Sakamoto, T. et al. (J Neurosci Res, 2003), Rezende, A. C. et al. (J Neurochem, 2009), Giess, R. et al. (Muscle Nerve, 1998)
Granulin precursor	GRN	M3YD29	Motor Neuron Disease	Baker, M. et al. (Nature, 2006) and 7 others Baker, M. et al. (Nature, 2006), Seelaar, H. et al. (Brain, 2007), Cairns, N. J. et al. (Am J Pathol, 2007), Mukherjee, O. et al. (Hum Mutat, 2008), Sleegers, K. et al. (Neurology, 2008), Pickering-Brown, S. M. et al. (Brain, 2008), Armstrong, R. A. et al. (J Neural Transm (Vienna), 2010), Robinson, A. C. et al. (Neuropathol Appl Neurobiol, 2014)
Granulins	Grn	P28798	Motor Neuron Disease	Baker, M. et al. (Nature, 2006) and 7 others Baker, M. et al. (Nature, 2006), Seelaar, H. et al. (Brain, 2007), Cairns, N. J. et al. (Am J Pathol, 2007), Mukherjee, O. et al. (Hum Mutat, 2008), Sleegers, K. et al. (Neurology, 2008), Pickering-Brown, S. M. et al. (Brain, 2008), Armstrong, R. A. et al. (J Neural Transm (Vienna), 2010), Robinson, A. C. et al. (Neuropathol Appl Neurobiol, 2014)
Glial cell line-derived neurotrophic factor	Gdnf	P48540	Motor Neuron Disease	Watabe, K. et al. (J Neurosci Res, 2000) and 2 others Watabe, K. et al. (J Neurosci Res, 2000), Wang, L. J. et al. (J Neurosci, 2002), Sakamoto, T. et al. (J Neurosci Res, 2003)
Valosin containing protein	VCP	M3XZQ1	Motor Neuron Disease	Cairns, N. J. et al. (Am J Pathol, 2007) and 3 others Cairns, N. J. et al. (Am J Pathol, 2007), Rohrer, J. D. et al. (Neurology, 2009), Gonzalez-Perez, P. et al. (Neurology, 2012), Yi, L. et al. (Ann N Y Acad Sci, 2014)
Transitional endoplasmic reticulum ATPase	Vcp	Q01853	Motor Neuron Disease	Cairns, N. J. et al. (Am J Pathol, 2007) and 3 others Cairns, N. J. et al. (Am J Pathol, 2007), Rohrer, J. D. et al. (Neurology, 2009), Gonzalez-Perez, P. et al. (Neurology, 2012), Yi, L. et al. (Ann N Y Acad Sci, 2014)
Transitional endoplasmic reticulum ATPase	Vcp	P46462	Motor Neuron Disease	Cairns, N. J. et al. (Am J Pathol, 2007) and 3 others Cairns, N. J. et al. (Am J Pathol, 2007), Rohrer, J. D. et al. (Neurology, 2009), Gonzalez-Perez, P. et al. (Neurology, 2012), Yi, L. et al. (Ann N Y Acad Sci, 2014)
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Pin1	Q9QUR7	Motor Neuron Disease	Dakson, A. et al. (Acta Neuropathol, 2011)
Tubulin-specific chaperone E	Tbce	Q8CIV8	Motor Neuron Disease	Martin, N. et al. (Nat Genet, 2002)
Protein/nucleic acid deglycase DJ-1	Park7	Q99LX0	Motor Neuron Disease	Annesi, G. et al. (Ann Neurol, 2005)
Parkinson disease protein 7 homolog	Park7	O88767	Motor Neuron Disease	Annesi, G. et al. (Ann Neurol, 2005)
Triggering receptor expressed on myeloid cells 2	Trem2	Q99NH8	Motor Neuron Disease	Forabosco, P. et al. (Neurobiol Aging, 2013)
Superoxide dismutase [Cu-Zn]	Sod1	P08228	Motor Neuron Disease, Lower	Wood-Allum, C. A. et al. (Brain, 2006), Saeed, M. et al. (Neurology, 2009)
Vimentin	VIM	M3YJK3	Motor Neuron Disease, Lower	Perrin, F. E. et al. (J Neurochem, 2006)
Vimentin	Vim	P20152	Motor Neuron Disease, Lower	Perrin, F. E. et al. (J Neurochem, 2006)
Vimentin	Vim	P31000	Motor Neuron Disease, Lower	Perrin, F. E. et al. (J Neurochem, 2006)
Vimentin	Vim	Q5FWJ3	Motor Neuron Disease, Lower	Perrin, F. E. et al. (J Neurochem, 2006)
Superoxide dismutase [Cu-Zn]	Sod1	P08228	Motor Neuron Disease, Secondary	Wood-Allum, C. A. et al. (Brain, 2006)
Vimentin	VIM	M3YJK3	Motor Neuron Disease, Secondary	Perrin, F. E. et al. (J Neurochem, 2006)
Vimentin	Vim	P20152	Motor Neuron Disease, Secondary	Perrin, F. E. et al. (J Neurochem, 2006)
Vimentin	Vim	P31000	Motor Neuron Disease, Secondary	Perrin, F. E. et al. (J Neurochem, 2006)
Vimentin	Vim	Q5FWJ3	Motor Neuron Disease, Secondary	Perrin, F. E. et al. (J Neurochem, 2006)
Superoxide dismutase [Cu-Zn]	Sod1	P08228	Motor Neuron Disease, Upper	Wood-Allum, C. A. et al. (Brain, 2006)

Brain-derived neurotrophic factor

Bdnf

P21237

Motor Neuron Disease

Sakamoto, T. et al. (J Neurosci Res, 2003)

Metallothionein-3

Mt3

P28184

Motor Neuron Disease

Sakamoto, T. et al. (Neuroreport, 2003), Watabe, K. et al. (Neuropathology, 2005)

Ciliary neurotrophic factor

Cntf