| Signal peptide(a) |
N |
Secretome P(b) |
0.0 |
| Function |
CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy. |
| GO - Molecular function |
- ciliary neurotrophic factor receptor binding : IPI:RGD
- cytokine activity : IDA:RGD
- growth factor activity : ISO:RGD
- interleukin-6 receptor binding : ISO:RGD
- protein-containing complex binding : IPI:RGD
|
| GO - Biological process |
- astrocyte activation : IDA:RGD
- ciliary neurotrophic factor-mediated signaling pathway : ISO:RGD
- membrane hyperpolarization : IDA:RGD
- muscle organ morphogenesis : ISO:RGD
- negative regulation of neuron apoptotic process : IDA:RGD
- negative regulation of neuron death : IDA:RGD
- negative regulation of photoreceptor cell differentiation : ISO:RGD
- nervous system development : IDA:RGD
- neuron development : ISO:RGD
- positive regulation of axon extension involved in regeneration : IDA:CAFA
- positive regulation of axon regeneration : IDA:RGD
- positive regulation of cell growth : IDA:RGD
- positive regulation of cell population proliferation : IDA:RGD
- positive regulation of gene expression : ISO:RGD
- positive regulation of hormone secretion : IDA:RGD
- positive regulation of MAPK cascade : IDA:RGD
- positive regulation of phosphatidylinositol 3-kinase signaling : IDA:RGD
- positive regulation of receptor signaling pathway via JAK-STAT : IDA:RGD
- positive regulation of tyrosine phosphorylation of STAT protein : IDA:RGD
- receptor signaling pathway via JAK-STAT : IDA:RGD
- regulation of resting membrane potential : IDA:RGD
- regulation of retinal cell programmed cell death : ISO:RGD
- response to electrical stimulus : IEP:RGD
- response to light intensity : IEP:RGD
|