Cathepsin Z (Q9WUU7)

Uniprot ID Q9WUU7
Protein Name Cathepsin Z
Gene Name Ctsz
Species Mus musculus (Mouse)
Signal peptide(a) Y Secretome P(b) 0.738
Function Exhibits carboxy-monopeptidase as well as carboxy-dipeptidase activity. .
GO - Molecular function
  • carboxypeptidase activity : ISO:MGI
  • cysteine-type endopeptidase activity : IBA:GO_Central
GO - Biological process
  • epithelial tube branching involved in lung morphogenesis : IEP:UniProtKB
  • negative regulation of neuron projection development : ISO:MGI
  • negative regulation of plasminogen activation : ISO:MGI
  • negative regulation of protein binding : ISO:MGI
  • positive regulation of neural precursor cell proliferation : ISO:MGI
  • positive regulation of neuron apoptotic process : ISO:MGI
  • proteolysis : ISO:MGI
  • proteolysis involved in cellular protein catabolic process : IBA:GO_Central
  • regulation of neuron death : ISO:MGI
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.