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P99024

Tubulin beta-5 chain (P99024)

Uniprot ID P99024
Protein Name Tubulin beta-5 chain
Gene Name Tubb5
Species Mus musculus (Mouse)
Basic Information Experiments (1) Disease (5) Interactions
Signal peptide(a) N Secretome P(b) 0.629
Function Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
GO - Molecular function
  • GTP binding : NAS:UniProtKB
  • GTPase activating protein binding : ISO:MGI
  • GTPase activity : IEA:InterPro
  • MHC class I protein binding : ISO:MGI
  • protein domain specific binding : ISO:MGI
  • protein-containing complex binding : ISO:MGI
  • structural constituent of cytoskeleton : IDA:MGI
  • ubiquitin protein ligase binding : ISO:MGI
GO - Biological process
  • cellular process : ISO:MGI
  • microtubule-based process : IDA:MGI
  • spindle assembly : IDA:MGI
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.