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Q9Z0K8

Pantetheinase (Q9Z0K8)

Uniprot ID Q9Z0K8
Protein Name Pantetheinase
Gene Name Vnn1
Species Mus musculus (Mouse)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) Y Secretome P(b) 0.775
Function Amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine. .
GO - Molecular function
  • GPI anchor binding : TAS:BHF-UCL
  • pantetheine hydrolase activity : ISS:UniProtKB
GO - Biological process
  • acute inflammatory response : IDA:BHF-UCL
  • cell-cell adhesion : IDA:BHF-UCL
  • chronic inflammatory response : IDA:BHF-UCL
  • inflammatory response : IMP:BHF-UCL
  • innate immune response : IDA:BHF-UCL
  • negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway : IMP:BHF-UCL
  • pantothenate metabolic process : ISS:UniProtKB
  • positive regulation of T cell differentiation in thymus : IDA:BHF-UCL
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.