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Q9Z0G4

WNT1-inducible-signaling pathway protein 2 (Q9Z0G4)

Uniprot ID Q9Z0G4
Protein Name WNT1-inducible-signaling pathway protein 2
Gene Name Wisp2
Species Mus musculus (Mouse)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) Y Secretome P(b) 0.0
Function May play an important role in modulating bone turnover. Promotes the adhesion of osteoblast cells and inhibits the binding of fibrinogen to integrin receptors. In addition, inhibits osteocalcin production (By similarity). .
GO - Molecular function
  • growth factor activity : ISA:MGI
  • heparin binding : IBA:GO_Central
  • insulin-like growth factor binding : IEA:InterPro
  • integrin binding : IBA:GO_Central
GO - Biological process
  • cell adhesion : IBA:GO_Central
  • cell-cell signaling : IBA:GO_Central
  • negative regulation of cell death : IBA:GO_Central
  • negative regulation of cell proliferation : ISO:MGI
  • regulation of cell growth : IDA:MGI
  • signal transduction : IBA:GO_Central
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.