PDZ domain-containing protein GIPC1 (Q9Z0G0)

Uniprot ID Q9Z0G0
Protein Name PDZ domain-containing protein GIPC1
Gene Name Gipc1
Species Mus musculus (Mouse)
Signal peptide(a) N Secretome P(b) 0.843
Function Inhibits endothelial cell migration (in vitro). May be involved in G protein-linked signaling (By similarity). .
GO - Molecular function
  • actin binding : IPI:MGI
  • cadherin binding : ISO:MGI
  • GTPase activator activity : TAS:MGI
  • identical protein binding : ISO:MGI
  • myosin binding : IPI:MGI
  • PDZ domain binding : ISO:MGI
  • protein homodimerization activity : IPI:MGI
  • signaling receptor binding : ISO:MGI
GO - Biological process
  • chemical synaptic transmission : IMP:MGI
  • endothelial cell migration : IMP:MGI
  • G-protein coupled receptor signaling pathway : TAS:MGI
  • glutamate secretion : IMP:MGI
  • negative regulation of proteasomal ubiquitin-dependent protein catabolic process : IDA:BHF-UCL
  • positive regulation of cytokinesis : ISO:MGI
  • positive regulation of transforming growth factor beta receptor signaling pathway : IDA:BHF-UCL
  • protein targeting : IMP:MGI
  • regulation of protein stability : IDA:BHF-UCL
  • regulation of synaptic plasticity : IMP:MGI
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.