Coronin-1C (Q9WUM4)

Uniprot ID Q9WUM4
Protein Name Coronin-1C
Gene Name Coro1c
Species Mus musculus (Mouse)
Signal peptide(a) N Secretome P(b) 0.658
Function May be involved in cytokinesis, motility, and signal transduction. .
GO - Molecular function
  • actin filament binding : ISO:MGI
  • Rac GTPase binding : IPI:UniProtKB
GO - Biological process
  • actin cortical patch assembly : TAS:MGI
  • actin cytoskeleton organization : TAS:MGI
  • activation of GTPase activity : IMP:UniProtKB
  • establishment of protein localization : IMP:UniProtKB
  • negative regulation of epithelial cell migration : ISO:MGI
  • negative regulation of focal adhesion assembly : ISO:MGI
  • negative regulation of protein kinase activity by regulation of protein phosphorylation : ISO:MGI
  • negative regulation of protein phosphorylation : ISO:MGI
  • negative regulation of substrate adhesion-dependent cell spreading : ISO:MGI
  • neural crest cell migration : ISO:MGI
  • phagocytosis : TAS:MGI
  • positive regulation of lamellipodium morphogenesis : ISO:MGI
  • regulation of epithelial cell migration : ISO:MGI
  • regulation of fibroblast migration : IMP:UniProtKB
  • regulation of focal adhesion assembly : ISO:MGI
  • regulation of protein phosphorylation : ISO:MGI
  • regulation of ruffle assembly : IGI:UniProtKB
  • regulation of substrate adhesion-dependent cell spreading : ISO:MGI
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.