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Q9WUA3

ATP-dependent 6-phosphofructokinase, platelet type (Q9WUA3)

Uniprot ID Q9WUA3
Protein Name ATP-dependent 6-phosphofructokinase, platelet type
Gene Name Pfkp
Species Mus musculus (Mouse)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) N Secretome P(b) 0.501
Function Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
GO - Molecular function
  • 6-phosphofructokinase activity : ISS:UniProtKB
  • ATP binding : ISO:MGI
  • cadherin binding : ISO:MGI
  • fructose-6-phosphate binding : ISO:MGI
  • identical protein binding : ISO:MGI
  • metal ion binding : IEA:UniProtKB-KW
  • protein-containing complex binding : ISO:MGI
GO - Biological process
  • cellular response to leukemia inhibitory factor : IEP:MGI
  • fructose 1,6-bisphosphate metabolic process : ISO:MGI
  • fructose 6-phosphate metabolic process : ISO:MGI
  • glycolytic process : ISO:MGI
  • glycolytic process through fructose-6-phosphate : ISS:MGI
  • protein homotetramerization : ISO:MGI
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.