| Signal peptide(a) |
Y |
Secretome P(b) |
0.551 |
| Function |
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. May act as a negative regulator of neural cell growth. |
| GO - Molecular function |
- adiponectin binding : IDA:BHF-UCL
- cadherin binding : ISO:MGI
- calcium ion binding : IEA:InterPro
- lipoprotein particle binding : ISO:MGI
- low-density lipoprotein particle binding : ISO:MGI
- protein homodimerization activity : IDA:MGI
|
| GO - Biological process |
- calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules : ISO:MGI
- endothelial cell migration : ISO:MGI
- homophilic cell adhesion via plasma membrane adhesion molecules : ISO:MGI
- keratinocyte proliferation : ISO:MGI
- lamellipodium assembly : ISO:MGI
- localization within membrane : ISO:MGI
- low-density lipoprotein particle mediated signaling : ISO:MGI
- mitotic cell cycle : IEA:Ensembl
- negative regulation of cell adhesion : ISO:MGI
- negative regulation of cell proliferation : ISO:MGI
- positive regulation of calcium-mediated signaling : ISO:MGI
- positive regulation of cell migration : ISO:MGI
- positive regulation of cell-matrix adhesion : ISO:MGI
- positive regulation of endothelial cell proliferation : ISO:MGI
- positive regulation of positive chemotaxis : ISO:MGI
- positive regulation of smooth muscle cell proliferation : ISO:MGI
- positive regulation of transcription by RNA polymerase II : ISO:MGI
- Rac protein signal transduction : ISO:MGI
- regulation of endocytosis : ISO:MGI
- regulation of epidermal growth factor receptor signaling pathway : ISO:MGI
- Rho protein signal transduction : ISO:MGI
- sprouting angiogenesis : ISO:MGI
|