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Q9WTQ5

A-kinase anchor protein 12 (Q9WTQ5)

Uniprot ID Q9WTQ5
Protein Name A-kinase anchor protein 12
Gene Name Akap12
Species Mus musculus (Mouse)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) N Secretome P(b) 0.242
Function Anchoring protein that mediates the subcellular compartmentation of protein kinase A (PKA) and protein kinase C (PKC). .
GO - Molecular function
  • adenylate cyclase binding : ISO:MGI
  • protein kinase A binding : IEA:InterPro
  • receptor signaling complex scaffold activity : TAS:MGI
GO - Biological process
  • adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway : ISO:MGI
  • positive regulation of protein kinase A signaling : IEA:InterPro
  • protein targeting : IEA:InterPro
  • regulation of protein kinase A signaling : ISO:MGI
  • regulation of protein kinase C signaling : IEA:InterPro
  • signal transduction : ISO:MGI
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.