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Q9ULW3

Activator of basal transcription 1 (Q9ULW3)

Uniprot ID Q9ULW3
Protein Name Activator of basal transcription 1
Gene Name ABT1
Species Homo sapiens (Human)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) N Secretome P(b) 0.702
Function Could be a novel TATA-binding protein (TBP) which can function as a basal transcription activator. Can act as a regulator of basal transcription for class II genes (By similarity). .
GO - Molecular function
  • DNA binding : IEA:UniProtKB-KW
  • RNA binding : HDA:UniProtKB
  • transcription coactivator activity : TAS:ProtInc
GO - Biological process
  • endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) : IBA:GO_Central
  • endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) : IBA:GO_Central
  • endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) : IBA:GO_Central
  • regulation of transcription by RNA polymerase II : IEA:Ensembl
  • small-subunit processome assembly : IBA:GO_Central
  • spinal cord motor neuron differentiation : IEA:Ensembl
  • transcription by RNA polymerase II : TAS:ProtInc
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(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.