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Q9UKP4

A disintegrin and metalloproteinase with thrombospondin motifs 7 (Q9UKP4)

Uniprot ID Q9UKP4
Protein Name A disintegrin and metalloproteinase with thrombospondin motifs 7
Gene Name ADAMTS7
Species Homo sapiens (Human)
Basic Information Experiments (2) Disease (0) Interactions
Signal peptide(a) Y Secretome P(b) 0.351
Function Metalloprotease that may play a role in the degradation of COMP. .
GO - Molecular function
  • metal ion binding : IEA:UniProtKB-KW
  • metalloendopeptidase activity : IDA:BHF-UCL
  • metallopeptidase activity : TAS:ProtInc
GO - Biological process
  • cellular response to BMP stimulus : IDA:BHF-UCL
  • cellular response to interleukin-1 : IMP:BHF-UCL
  • cellular response to tumor necrosis factor : IMP:BHF-UCL
  • negative regulation of chondrocyte differentiation : IDA:BHF-UCL
  • proteolysis involved in cellular protein catabolic process : IMP:BHF-UCL
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.