Carboxypeptidase A4 (Q9UI42)

Uniprot ID Q9UI42
Protein Name Carboxypeptidase A4
Gene Name CPA4
Species Homo sapiens (Human)
Signal peptide(a) N Secretome P(b) 0.764
Function Metalloprotease that could be involved in the histone hyperacetylation pathway (PubMed:10383164). Releases a C-terminal amino acid, with preference for -Phe, -Leu, -Ile, -Met, -Tyr and -Val (PubMed:20385563). .
GO - Molecular function
  • metallocarboxypeptidase activity : IBA:GO_Central
  • zinc ion binding : IEA:InterPro
GO - Biological process
  • histone acetylation : NAS:UniProtKB
  • proteolysis : IBA:GO_Central
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.