Enolase-phosphatase E1 (Q9UHY7)

Uniprot ID Q9UHY7
Protein Name Enolase-phosphatase E1
Gene Name ENOPH1
Species Homo sapiens (Human)
Signal peptide(a) N Secretome P(b) 0.734
Function Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). .
GO - Molecular function
  • acireductone synthase activity : IDA:UniProtKB
  • magnesium ion binding : IEA:InterPro
GO - Biological process
  • L-methionine salvage from methylthioadenosine : IDA:UniProtKB
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.