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Q9R0B9

Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 (Q9R0B9)

Uniprot ID Q9R0B9
Protein Name Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2
Gene Name Plod2
Species Mus musculus (Mouse)
Basic Information Experiments (5) Disease (0) Interactions
Signal peptide(a) Y Secretome P(b) 0.552
Function Forms hydroxylysine residues in -Xaa-Lys-Gly-sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links. .
GO - Molecular function
  • iron ion binding : IEA:InterPro
  • L-ascorbic acid binding : IEA:UniProtKB-KW
  • procollagen-lysine 5-dioxygenase activity : ISO:MGI
GO - Biological process
  • hydroxylysine biosynthetic process : ISO:MGI
  • peptidyl-lysine hydroxylation : ISO:MGI
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(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.