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Q9R087

Glypican-6 (Q9R087)

Uniprot ID Q9R087
Protein Name Glypican-6
Gene Name Gpc6
Species Mus musculus (Mouse)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) Y Secretome P(b) 0.493
Function Cell surface proteoglycan that bears heparan sulfate. Putative cell surface coreceptor for growth factors, extracellular matrix proteins, proteases and anti-proteases. Enhances migration and invasion of cancer cells through WNT5A signaling (By similarity). .
GO - Molecular function
GO - Biological process
  • cell migration : ISS:UniProtKB
  • regulation of neurotransmitter receptor localization to postsynaptic specialization membrane : ISO:MGI
  • regulation of presynapse assembly : IBA:GO_Central
  • regulation of protein localization to membrane : IBA:GO_Central
  • regulation of signal transduction : IEA:InterPro
  • synaptic membrane adhesion : IBA:GO_Central
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(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.