| Signal peptide(a) |
N |
Secretome P(b) |
|
| Function |
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. . |
| GO - Molecular function |
- antioxidant activity : ISO:RGD
- cysteine-type endopeptidase inhibitor activity involved in apoptotic process : ISO:RGD
- peroxidase activity : ISO:RGD
- peroxiredoxin activity : ISO:RGD
- peroxynitrite reductase activity : ISO:RGD
- protein dimerization activity : ISO:RGD
- RNA polymerase III regulatory region DNA binding : ISO:RGD
- signaling receptor binding : ISO:RGD
- thioredoxin peroxidase activity : ISO:RGD
|
| GO - Biological process |
- cell redox homeostasis : IBA:GO_Central
- cellular response to oxidative stress : IBA:GO_Central
- cellular response to reactive oxygen species : ISO:RGD
- hydrogen peroxide catabolic process : ISO:RGD
- NADPH oxidation : ISO:RGD
- negative regulation of apoptotic process : ISO:RGD
- negative regulation of oxidoreductase activity : ISO:RGD
- negative regulation of transcription by RNA polymerase III : ISO:RGD
- positive regulation of collagen biosynthetic process : ISO:RGD
- reactive nitrogen species metabolic process : ISO:RGD
- regulation of apoptosis involved in tissue homeostasis : ISO:RGD
- response to oxidative stress : ISO:RGD
|