NTF2-related export protein 1 (Q9QZV9)

Uniprot ID Q9QZV9
Protein Name NTF2-related export protein 1
Gene Name Nxt1
Species Mus musculus (Mouse)
Signal peptide(a) N Secretome P(b) 0.756
Function Stimulator of protein export for NES-containing proteins. Also plays a role in the nuclear export of U1 snRNA, tRNA, and mRNA. The NXF1-NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with ALYREF/THOC4 and THOC5 (By similarity). .
GO - Molecular function
  • Ran GTPase binding : IDA:MGI
GO - Biological process
  • mRNA transport : IEA:UniProtKB-KW
  • protein export from nucleus : IDA:MGI
  • RNA export from nucleus : IDA:MGI
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.