Collagen alpha-4(IV) chain (Q9QZR9)

Uniprot ID Q9QZR9
Protein Name Collagen alpha-4(IV) chain
Gene Name Col4a4
Species Mus musculus (Mouse)
Signal peptide(a) N Secretome P(b) 0.057
Function Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen. .
GO - Molecular function
  • extracellular matrix structural constituent : IPI:UniProtKB
GO - Biological process
  • collagen-activated tyrosine kinase receptor signaling pathway : IBA:GO_Central
  • extracellular matrix organization : IBA:GO_Central
  • glomerular basement membrane development : IMP:MGI
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(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.