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Q9QZ08

N-acetyl-D-glucosamine kinase (Q9QZ08)

Uniprot ID Q9QZ08
Protein Name N-acetyl-D-glucosamine kinase
Gene Name Nagk
Species Mus musculus (Mouse)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) N Secretome P(b) 0.794
Function Converts endogenous N-acetylglucosamine (GlcNAc), a major component of complex carbohydrates, from lysosomal degradation or nutritional sources into GlcNAc 6-phosphate. Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway. Also has ManNAc kinase activity. .
GO - Molecular function
  • ATP binding : IEA:UniProtKB-KW
  • N-acetylglucosamine kinase activity : IDA:MGI
  • N-acylmannosamine kinase activity : IDA:MGI
GO - Biological process
  • N-acetylglucosamine metabolic process : IDA:MGI
  • N-acetylneuraminate catabolic process : TAS:UniProtKB
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.