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Q9QYP2

Cadherin EGF LAG seven-pass G-type receptor 2 (Q9QYP2)

Uniprot ID Q9QYP2
Protein Name Cadherin EGF LAG seven-pass G-type receptor 2
Gene Name Celsr2
Species Rattus norvegicus (Rat)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) N Secretome P(b)
Function Receptor that may have an important role in cell/cell signaling during nervous system formation.
GO - Molecular function
  • calcium ion binding : IEA:InterPro
  • G protein-coupled receptor activity : IEA:UniProtKB-KW
GO - Biological process
  • cell-cell adhesion : IBA:GO_Central
  • cerebrospinal fluid secretion : ISO:RGD
  • cilium assembly : ISO:RGD
  • cilium movement : ISO:RGD
  • dendrite morphogenesis : IMP:BHF-UCL
  • homophilic cell adhesion via plasma membrane adhesion molecules : ISO:RGD
  • neural plate anterior/posterior regionalization : ISO:RGD
  • neuron migration : ISO:RGD
  • regulation of cell-cell adhesion : IMP:BHF-UCL
  • regulation of protein localization : ISO:RGD
  • regulation of transcription, DNA-templated : ISO:RGD
  • spermatogenesis : IEP:RGD
  • ventricular system development : ISO:RGD
  • Wnt signaling pathway : ISO:RGD
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(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.