Tomoregulin-2 (Q9QYM9)

Uniprot ID Q9QYM9
Protein Name Tomoregulin-2
Gene Name Tmeff2
Species Mus musculus (Mouse)
Signal peptide(a) Y Secretome P(b) 0.426
Function May be a survival factor for hippocampal and mesencephalic neurons. The shedded form may up-regulate cell proliferation (By similarity). .
GO - Molecular function
GO - Biological process
  • negative regulation of cell migration : ISO:MGI
  • negative regulation of integrin biosynthetic process : ISO:MGI
  • negative regulation of stress fiber assembly : ISO:MGI
  • wound healing, spreading of cells : ISO:MGI
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.