| Signal peptide(a) |
N |
Secretome P(b) |
0.112 |
| Function |
Drebrins might play some role in cell migration, extension of neuronal processes and plasticity of dendrites. Required for actin polymerization at immunological synapses (IS) and for CXCR4 recruitment to IS. . |
| GO - Molecular function |
- actin filament binding : ISO:MGI
- cadherin binding : ISO:MGI
- cytoskeletal protein binding : ISO:MGI
- profilin binding : ISS:UniProtKB
|
| GO - Biological process |
- actin filament organization : IDA:MGI
- cell communication by chemical coupling : IMP:MGI
- cell communication by electrical coupling : IMP:MGI
- cellular response to transforming growth factor beta stimulus : ISO:MGI
- cellular response to tumor necrosis factor : ISO:MGI
- generation of neurons : IEP:DFLAT
- maintenance of protein location in cell : IMP:MGI
- modulation of inhibitory postsynaptic potential : ISO:MGI
- negative regulation of actin filament bundle assembly : ISO:MGI
- negative regulation of actin-dependent ATPase activity : ISO:MGI
- negative regulation of locomotion involved in locomotory behavior : ISO:MGI
- negative regulation of muscle filament sliding : ISO:MGI
- neural precursor cell proliferation : IEP:DFLAT
- positive regulation of axon extension : ISO:MGI
- positive regulation of cell-substrate adhesion : ISO:MGI
- positive regulation of dendritic spine morphogenesis : ISO:MGI
- positive regulation of excitatory postsynaptic potential : ISO:MGI
- positive regulation of neuron projection development : ISO:MGI
- positive regulation of substrate adhesion-dependent cell spreading : ISO:MGI
- prepulse inhibition : ISO:MGI
- regulation of actin filament polymerization : ISO:MGI
- regulation of filopodium assembly : ISO:MGI
- regulation of postsynaptic density protein 95 clustering : ISO:MGI
|