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Q9QWN8

Spectrin beta chain, non-erythrocytic 2 (Q9QWN8)

Uniprot ID Q9QWN8
Protein Name Spectrin beta chain, non-erythrocytic 2
Gene Name Sptbn2
Species Rattus norvegicus (Rat)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) N Secretome P(b)
Function Probably plays an important role in neuronal membrane skeleton.
GO - Molecular function
  • actin binding : IEA:UniProtKB-KW
  • phospholipid binding : IEA:InterPro
  • structural constituent of cytoskeleton : TAS:UniProtKB
  • structural constituent of synapse : ISO:RGD
GO - Biological process
  • actin filament capping : IEA:UniProtKB-KW
  • adult behavior : ISO:RGD
  • cellular response to ethanol : IEP:RGD
  • cerebellar Purkinje cell layer morphogenesis : ISO:RGD
  • multicellular organism growth : ISO:RGD
  • postsynapse organization : ISO:RGD
  • regulation of calcium ion-dependent exocytosis : TAS:UniProtKB
  • synapse assembly : ISO:RGD
  • synaptic vesicle docking : TAS:UniProtKB
  • synaptic vesicle exocytosis : IPI:UniProtKB
  • vesicle-mediated transport : ISO:RGD
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(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.