Cysteine-rich motor neuron 1 protein (Q9NZV1)

Uniprot ID Q9NZV1
Protein Name Cysteine-rich motor neuron 1 protein
Gene Name CRIM1
Species Homo sapiens (Human)
Signal peptide(a) Y Secretome P(b) 0.443
Function May play a role in CNS development by interacting with growth factors implicated in motor neuron differentiation and survival. May play a role in capillary formation and maintenance during angiogenesis. Modulates BMP activity by affecting its processing and delivery to the cell surface. .
GO - Molecular function
  • insulin-like growth factor binding : IEA:InterPro
  • insulin-like growth factor-activated receptor activity : TAS:ProtInc
  • PDZ domain binding : IDA:MGI
  • serine-type endopeptidase inhibitor activity : IEA:InterPro
GO - Biological process
  • nervous system development : TAS:ProtInc
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.