Podocalyxin-like protein 2 (Q9NZ53)

Uniprot ID Q9NZ53
Protein Name Podocalyxin-like protein 2
Gene Name PODXL2
Species Homo sapiens (Human)
Signal peptide(a) N Secretome P(b) 0.234
Function Acts as a ligand for vascular selectins. Mediates rapid rolling of leukocytes over vascular surfaces through high affinity divalent cation-dependent interactions with E-, P-and L-selectins. .
GO - Molecular function
  • glycosaminoglycan binding : TAS:ProtInc
GO - Biological process
  • leukocyte tethering or rolling : IDA:UniProtKB
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.