Heme-binding protein 1 (Q9NRV9)

Uniprot ID Q9NRV9
Protein Name Heme-binding protein 1
Gene Name HEBP1
Species Homo sapiens (Human)
Signal peptide(a) N Secretome P(b) 0.753
Function May bind free porphyrinogens that may be present in the cell and thus facilitate removal of these potentially toxic compound. Binds with a high affinity to one molecule of heme or porphyrins. It binds metalloporphyrins, free porphyrins and N-methylprotoporphyrin with similar affinities. .
GO - Molecular function
  • heme binding : ISS:UniProtKB
GO - Biological process
  • circadian rhythm : TAS:ProtInc
  • G-protein coupled receptor signaling pathway : TAS:Reactome
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(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.