| Signal peptide(a) |
N |
Secretome P(b) |
|
| Function |
Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2. During cell spreading, plays an important role in cytoskeleton reorganization, focal contacts formation (in the central part but not the margins of spreading cells), and lamellipodial extension; this function is mechanically antagonized by MYH9 (By similarity). Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. . |
| GO - Molecular function |
- actin filament binding : ISO:RGD
- actin-dependent ATPase activity : ISO:RGD
- ADP binding : ISO:RGD
- ATP binding : ISO:RGD
- ATPase activity : ISO:RGD
- calmodulin binding : IEA:UniProtKB-KW
- identical protein binding : IDA:RGD
- microfilament motor activity : ISO:RGD
- mRNA 5'-UTR binding : ISO:RGD
- RNA stem-loop binding : ISO:RGD
|
| GO - Biological process |
- actin cytoskeleton organization : ISO:RGD
- actin filament bundle assembly : IMP:RGD
- actin filament bundle distribution : IMP:RGD
- actin filament-based movement : ISO:RGD
- actomyosin structure organization : ISO:RGD
- adult heart development : ISO:RGD
- aorta development : ISO:RGD
- axon guidance : ISO:RGD
- axonogenesis : ISO:RGD
- brain development : IEP:RGD
- cardiac myofibril assembly : ISO:RGD
- cardiac septum development : ISO:RGD
- cell adhesion : IDA:RGD
- cell population proliferation : ISO:RGD
- cerebellar Purkinje cell layer development : ISO:RGD
- coronary vasculature development : ISO:RGD
- exocytosis : ISO:RGD
- fourth ventricle development : ISO:RGD
- heart development : ISO:RGD
- in utero embryonic development : ISO:RGD
- lateral ventricle development : ISO:RGD
- mitotic cytokinesis : ISO:RGD
- myofibril assembly : ISO:RGD
- neuromuscular process controlling balance : ISO:RGD
- neuron migration : ISO:RGD
- neuron projection development : ISO:RGD
- nuclear migration : ISO:RGD
- plasma membrane repair : ISO:RGD
- positive regulation of protein secretion : ISO:RGD
- postsynaptic actin cytoskeleton organization : ISO:RGD
- regulation of cell shape : ISO:RGD
- regulation of modification of postsynaptic actin cytoskeleton : IDA:SynGO
- retina development in camera-type eye : ISO:RGD
- substrate-dependent cell migration, cell extension : ISO:RGD
- third ventricle development : ISO:RGD
- ventricular cardiac muscle cell development : ISO:RGD
|