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Q9JKL8

Activity-dependent neuroprotector homeobox protein (Q9JKL8)

Uniprot ID Q9JKL8
Protein Name Activity-dependent neuroprotector homeobox protein
Gene Name Adnp
Species Rattus norvegicus (Rat)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) N Secretome P(b) 0.403
Function Potential transcription factor. May mediate some of the neuroprotective peptide VIP-associated effects involving normal growth and cancer proliferation.
GO - Molecular function
  • beta-tubulin binding : IPI:RGD
  • chromatin binding : ISO:RGD
  • copper ion binding : IDA:RGD
  • DNA binding : IEA:UniProtKB-KW
  • peptide binding : IDA:RGD
GO - Biological process
  • activation of protein kinase activity : IDA:RGD
  • cellular response to extracellular stimulus : IEP:RGD
  • cGMP-mediated signaling : IDA:RGD
  • estrous cycle : IEP:RGD
  • negative regulation of gene expression : IDA:RGD
  • negative regulation of neuron apoptotic process : IDA:RGD
  • negative regulation of protein binding : IDA:RGD
  • negative regulation of synaptic transmission : IMP:RGD
  • nitric oxide homeostasis : IDA:RGD
  • positive regulation of axon extension : IDA:RGD
  • positive regulation of neuron projection development : IDA:RGD
  • positive regulation of peptidyl-tyrosine phosphorylation : IDA:RGD
  • positive regulation of synapse assembly : IDA:RGD
  • regulation of protein ADP-ribosylation : IDA:RGD
  • response to carbohydrate : IEP:RGD
  • response to inorganic substance : IEP:RGD
  • short-term memory : IDA:RGD
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.