Spondin-1 (Q9HCB6)

Uniprot ID Q9HCB6
Protein Name Spondin-1
Gene Name SPON1
Species Homo sapiens (Human)
Signal peptide(a) Y Secretome P(b) 0.374
Function Cell adhesion protein that promotes the attachment of spinal cord and sensory neuron cells and the outgrowth of neurites in vitro. May contribute to the growth and guidance of axons in both the spinal cord and the PNS (By similarity). Major factor for vascular smooth muscle cell. .
GO - Molecular function
  • metal ion binding : IEA:UniProtKB-KW
GO - Biological process
  • cell adhesion : IEA:UniProtKB-KW
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(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.