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Q9HB71

Calcyclin-binding protein (Q9HB71)

Uniprot ID Q9HB71
Protein Name Calcyclin-binding protein
Gene Name CACYBP
Species Homo sapiens (Human)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) N Secretome P(b) 0.779
Function May be involved in calcium-dependent ubiquitination and subsequent proteasomal degradation of target proteins. Probably serves as a molecular bridge in ubiquitin E3 complexes. Participates in the ubiquitin-mediated degradation of beta-catenin (CTNNB1). .
GO - Molecular function
  • protein domain specific binding : IEA:Ensembl
  • protein homodimerization activity : IPI:UniProtKB
  • S100 protein binding : IEA:InterPro
  • tubulin binding : IEA:InterPro
  • ubiquitin protein ligase binding : IEA:Ensembl
GO - Biological process
  • aging : IEA:Ensembl
  • cardiac muscle cell differentiation : IEA:Ensembl
  • cellular response to calcium ion : IEA:Ensembl
  • cellular response to leukemia inhibitory factor : IEA:Ensembl
  • negative regulation of cell death : IEA:Ensembl
  • positive regulation of DNA replication : IEA:Ensembl
  • response to growth hormone : IEA:Ensembl
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.