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Q9H4A4

Aminopeptidase B (Q9H4A4)

Uniprot ID Q9H4A4
Protein Name Aminopeptidase B
Gene Name RNPEP
Species Homo sapiens (Human)
Basic Information Experiments (2) Disease (0) Interactions
Signal peptide(a) N Secretome P(b) 0.659
Function Exopeptidase which selectively removes arginine and/or lysine residues from the N-terminus of several peptide substrates including Arg(0)-Leu-enkephalin, Arg(0)-Met-enkephalin and Arg(-1)-Lys(0)-somatostatin-14. Can hydrolyze leukotriene A4 (LTA-4) into leukotriene B4 (LTB-4) (By similarity). .
GO - Molecular function
  • aminopeptidase activity : ISS:UniProtKB
  • epoxide hydrolase activity : NAS:UniProtKB
  • metalloaminopeptidase activity : IBA:GO_Central
  • metalloexopeptidase activity : NAS:UniProtKB
  • peptide binding : IBA:GO_Central
  • zinc ion binding : IBA:GO_Central
GO - Biological process
  • negative regulation of blood pressure : IBA:GO_Central
  • peptide catabolic process : IBA:GO_Central
  • proteolysis : IBA:GO_Central
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.