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Q9H3U7

SPARC-related modular calcium-binding protein 2 (Q9H3U7)

Uniprot ID Q9H3U7
Protein Name SPARC-related modular calcium-binding protein 2
Gene Name SMOC2
Species Homo sapiens (Human)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) Y Secretome P(b) 0.405
Function Promotes matrix assembly and cell adhesiveness (By similarity). Can stimulate endothelial cell proliferation, migration, as well as angiogenesis. .
GO - Molecular function
  • calcium ion binding : ISA:UniProtKB
  • heparin binding : IEA:Ensembl
GO - Biological process
  • extracellular matrix organization : IEA:Ensembl
  • positive regulation of angiogenesis : IDA:UniProtKB
  • positive regulation of cell-substrate adhesion : IEA:Ensembl
  • positive regulation of DNA biosynthetic process : IDA:UniProtKB
  • positive regulation of endothelial cell chemotaxis : IGI:UniProtKB
  • positive regulation of endothelial cell migration : IDA:UniProtKB
  • positive regulation of fibroblast growth factor receptor signaling pathway : IDA:UniProtKB
  • positive regulation of mitotic cell cycle : IDA:UniProtKB
  • positive regulation of vascular endothelial growth factor signaling pathway : IDA:UniProtKB
  • positive regulation of vascular wound healing : IDA:UniProtKB
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.