Nucleotide exchange factor SIL1 (Q9H173)

Uniprot ID	Q9H173
Protein Name	Nucleotide exchange factor SIL1
Gene Name	SIL1
Species	Homo sapiens (Human)

Signal peptide^(a)	Y	Secretome P^(b)	0.589
Function	Required for protein translocation and folding in the endoplasmic reticulum (ER). Functions as a nucleotide exchange factor for the ER lumenal chaperone HSPA5. .
GO - Molecular function	unfolded protein binding : NAS:UniProtKB
GO - Biological process	intracellular protein transport : NAS:UniProtKB protein folding : NAS:UniProtKB

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^{(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.}
^{(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.}