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Q9ES30

Complement C1q tumor necrosis factor-related protein 3 (Q9ES30)

Uniprot ID Q9ES30
Protein Name Complement C1q tumor necrosis factor-related protein 3
Gene Name C1qtnf3
Species Mus musculus (Mouse)
Basic Information Experiments (1) Disease (1) Interactions
Signal peptide(a) Y Secretome P(b) 0.645
Function
GO - Molecular function
  • identical protein binding : IDA:MGI
GO - Biological process
  • cellular triglyceride homeostasis : ISO:MGI
  • glucose homeostasis : IDA:MGI
  • negative regulation of gene expression : ISO:MGI
  • negative regulation of gluconeogenesis : IDA:MGI
  • negative regulation of inflammatory response : ISO:MGI
  • negative regulation of interleukin-6 secretion : ISO:MGI
  • negative regulation of monocyte chemotactic protein-1 production : ISO:MGI
  • negative regulation of NIK/NF-kappaB signaling : ISO:MGI
  • positive regulation of adiponectin secretion : IDA:UniProtKB
  • positive regulation of cytokine secretion : IDA:UniProtKB
  • positive regulation of ERK1 and ERK2 cascade : IDA:MGI
  • positive regulation of protein kinase B signaling : IDA:MGI
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.