14 kDa phosphohistidine phosphatase (Q9DAK9)

Uniprot ID Q9DAK9
Protein Name 14 kDa phosphohistidine phosphatase
Gene Name Phpt1
Species Mus musculus (Mouse)
Signal peptide(a) N Secretome P(b) 0.758
Function Exhibits phosphohistidine phosphatase activity. .
GO - Molecular function
  • calcium channel inhibitor activity : ISO:MGI
  • ion channel binding : ISO:MGI
  • protein histidine phosphatase activity : ISO:MGI
GO - Biological process
  • negative regulation of ATP citrate synthase activity : ISO:MGI
  • negative regulation of lyase activity : ISO:MGI
  • negative regulation of T cell receptor signaling pathway : ISO:MGI
  • peptidyl-histidine dephosphorylation : ISO:MGI
  • positive regulation of cell motility : IMP:BHF-UCL
  • positive regulation of insulin secretion involved in cellular response to glucose stimulus : ISO:MGI
  • protein dephosphorylation : ISO:MGI
  • regulation of actin cytoskeleton reorganization : ISO:MGI
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(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.