Home Proteins Experiments Diseases Interactions Tutorial
Home
/
Proteins
/
Q9D7G0

Ribose-phosphate pyrophosphokinase 1 (Q9D7G0)

Uniprot ID Q9D7G0
Protein Name Ribose-phosphate pyrophosphokinase 1
Gene Name Prps1
Species Mus musculus (Mouse)
Basic Information Experiments (2) Disease (6) Interactions
Signal peptide(a) N Secretome P(b) 0.675
Function Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.
GO - Molecular function
  • ADP binding : ISO:MGI
  • AMP binding : ISO:MGI
  • ATP binding : ISS:UniProtKB
  • carbohydrate binding : ISO:MGI
  • GDP binding : ISO:MGI
  • identical protein binding : ISO:MGI
  • kinase activity : IEA:UniProtKB-KW
  • magnesium ion binding : ISO:MGI
  • protein homodimerization activity : ISS:UniProtKB
  • ribose phosphate diphosphokinase activity : ISS:UniProtKB
GO - Biological process
  • 5-phosphoribose 1-diphosphate biosynthetic process : ISO:MGI
  • AMP biosynthetic process : ISO:MGI
  • hypoxanthine biosynthetic process : ISO:MGI
  • nervous system development : ISO:MGI
  • nucleoside metabolic process : IEA:InterPro
  • nucleotide biosynthetic process : ISO:MGI
  • purine nucleobase metabolic process : ISO:MGI
  • purine nucleotide biosynthetic process : ISO:MGI
  • ribose phosphate metabolic process : ISO:MGI
  • urate biosynthetic process : ISO:MGI
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.