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Q9BYN0

Sulfiredoxin-1 (Q9BYN0)

Uniprot ID Q9BYN0
Protein Name Sulfiredoxin-1
Gene Name SRXN1
Species Homo sapiens (Human)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) N Secretome P(b) 0.929
Function Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in the peroxiredoxins PRDX1, PRDX2, PRDX3 and PRDX4. Does not act on PRDX5 or PRDX6. May catalyze the reduction in a multi-step process by acting both as a specific phosphotransferase and a thioltransferase. .
GO - Molecular function
  • ATP binding : IEA:UniProtKB-KW
  • oxidoreductase activity, acting on a sulfur group of donors : IDA:UniProtKB
  • sulfiredoxin activity : IBA:GO_Central
GO - Biological process
  • cellular response to oxidative stress : IBA:GO_Central
  • response to oxidative stress : IDA:UniProtKB
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.