AP-1 complex subunit mu-1 (Q9BXS5)

Uniprot ID Q9BXS5
Protein Name AP-1 complex subunit mu-1
Gene Name AP1M1
Species Homo sapiens (Human)
Signal peptide(a) N Secretome P(b) 0.732
Function Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
GO - Molecular function
GO - Biological process
  • antigen processing and presentation of exogenous peptide antigen via MHC class II : TAS:Reactome
  • endosome to melanosome transport : IMP:UniProtKB
  • intracellular protein transport : IEA:InterPro
  • melanosome organization : IMP:UniProtKB
  • neutrophil degranulation : TAS:Reactome
  • regulation of defense response to virus by virus : TAS:Reactome
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.