Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q (Q9BRB3)

Uniprot ID Q9BRB3
Protein Name Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q
Gene Name PIGQ
Species Homo sapiens (Human)
Signal peptide(a) N Secretome P(b) 0.42
Function Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.
GO - Molecular function
  • phosphatidylinositol N-acetylglucosaminyltransferase activity : IEA:UniProtKB-EC
GO - Biological process
  • carbohydrate metabolic process : TAS:ProtInc
  • preassembly of GPI anchor in ER membrane : TAS:Reactome
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(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.