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Q99J86

Attractin (Q99J86)

Uniprot ID Q99J86
Protein Name Attractin
Gene Name Atrn
Species Rattus norvegicus (Rat)
Basic Information Experiments (2) Disease (1) Interactions
Signal peptide(a) N Secretome P(b)
Function Involved in the initial immune cell clustering during inflammatory response and may regulate chemotactic activity of chemokines (By similarity). May play a role in melanocortin signaling pathways that regulate energy homeostasis and hair color. Low-affinity receptor for agouti (By similarity). Has a critical role in normal myelination in the central nervous system. .
GO - Molecular function
  • carbohydrate binding : IEA:UniProtKB-KW
  • signaling receptor activity : ISO:RGD
GO - Biological process
  • animal organ morphogenesis : IBA:GO_Central
  • cerebellum development : ISO:RGD
  • inflammatory response : IEA:UniProtKB-KW
  • myelination : ISO:RGD
  • pigmentation : IMP:CACAO
  • regulation of multicellular organism growth : ISO:RGD
  • response to oxidative stress : IMP:RGD
  • tissue development : IBA:GO_Central
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(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.