Endophilin-A2 (Q99961)

Uniprot ID Q99961
Protein Name Endophilin-A2
Gene Name SH3GL1
Species Homo sapiens (Human)
Signal peptide(a) N Secretome P(b) 0.894
Function Implicated in endocytosis. May recruit other proteins to membranes with high curvature (By similarity). .
GO - Molecular function
  • beta-1 adrenergic receptor binding : IEA:Ensembl
  • cadherin binding : HDA:BHF-UCL
  • GTPase binding : IEA:Ensembl
  • identical protein binding : IPI:IntAct
  • ion channel binding : IEA:Ensembl
  • lipid binding : IEA:UniProtKB-KW
  • phosphatase binding : IEA:Ensembl
  • protein C-terminus binding : IEA:Ensembl
  • SH3 domain binding : IEA:Ensembl
GO - Biological process
  • central nervous system development : TAS:ProtInc
  • modulation of excitatory postsynaptic potential : IEA:Ensembl
  • positive regulation of synaptic vesicle endocytosis : IEA:Ensembl
  • signal transduction : TAS:ProtInc
  • synaptic vesicle uncoating : IEA:Ensembl
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.