PDZ and LIM domain protein 2 (Q96JY6)

Uniprot ID Q96JY6
Protein Name PDZ and LIM domain protein 2
Gene Name PDLIM2
Species Homo sapiens (Human)
Signal peptide(a) N Secretome P(b) 0.608
Function Probable adapter protein located at the actin cytoskeleton that promotes cell attachment. Necessary for the migratory capacity of epithelial cells. Overexpression enhances cell adhesion to collagen and fibronectin and suppresses anchorage independent growth. May contribute to tumor cell migratory capacity. .
GO - Molecular function
  • metal ion binding : IEA:UniProtKB-KW
GO - Biological process
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.