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Q96GW7

Brevican core protein (Q96GW7)

Uniprot ID Q96GW7
Protein Name Brevican core protein
Gene Name BCAN
Species Homo sapiens (Human)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) N Secretome P(b) 0.504
Function May play a role in the terminally differentiating and the adult nervous system during postnatal development. Could stabilize interactions between hyaluronan (HA) and brain proteoglycans.
GO - Molecular function
  • carbohydrate binding : IEA:UniProtKB-KW
  • hyaluronic acid binding : IEA:UniProtKB-KW
GO - Biological process
  • cell adhesion : IEA:InterPro
  • central nervous system development : IBA:GO_Central
  • chondroitin sulfate biosynthetic process : TAS:Reactome
  • chondroitin sulfate catabolic process : TAS:Reactome
  • dermatan sulfate biosynthetic process : TAS:Reactome
  • extracellular matrix organization : TAS:Reactome
  • hippocampus development : IEA:Ensembl
  • skeletal system development : IBA:GO_Central
  • synapse maturation : IEA:Ensembl
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(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.